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13/01/2025
Here's one of my ironclad rules. When a new drug/medication hits the market, I avoid it like the plague for at least 1-3 years.
Why?
So I can see if it is likely to cause harm, adverse reactions, etc. You must understand that all of the initial research for new medications is done with small numbers of animals, and often misses side effects that only pop up when larger numbers of animals are exposed to the treatment.
This new arthritis medication blocks Nerve Growth factor (NGF) which has a reasonable efficacy in reducing arthritic pain.
The big problem is that NGF is found in lots of tissues and organs throughout the body, AND it's super important for the healthy functioning of the immune system, the nervous system, gut, - and really, the whole body!
So it's not surprising to me that so many dogs are experiencing serious adverse reactions. With two doses, the chances of an adverse reaction are about 1 in 550. The more doses (and it's a monthly injection), the higher the chances of harm/injury become.
I think there is a place for this medication as a 'drug of last resort' to extend life when we have done everything else. No way would I give it to my dogs unless this were the case.
However - the company that makes it is aggressively marketing this as a 'wonder drug, totally safe, side effect free'. This is what they are telling vets.
Also, the product insert in some countries list more side effects/adverse reactions than in other countries. This means vets are not being told the possible risks, and they might then recommend this medication for your dogs on the basis of what they know, which is not the full picture.
I'm personally amazed that this drug has been approved. The exact same thing for humans was not, because of the high risk of adverse reactions compared to other readily available arthritis treatments.
My advice? Avoid unless you're out of options!
I help animals all over the world heal and be well + happy with holistic veterinary care, kind training, and energy healing. If you want me to help your pets, message me! Zoom and in person appts available.