17/10/2025
Yesterday's post seems to have been quite popular! I made quite a few comments that I claimed were backed up with research, and particularly as what I'm saying is a little controversial, I thought I would dig up some of the studies I'm referring to (and this isn't all of them).
Most of the time when people (experts) say that obesity causes insulin resistance/laminitis they refer back to larger scale field studies that find that obesity is linked with insulin levels going up/resistance or laminitis. But this doesn't tell us which came first! So as someone who was trained in basic experimental research, I look to the controlled experiments where horses were overfed caloriess to induce obesity, to look for the chicken and the egg - results below.
Warning. Long.
NOTE: I have read all of these studies in full at various points in time, but I admit that I have used AI tools to put it together and compose this post because I simply did not have time to do it all myself! Image is my brain trying to organise it into an easy to understand format and failing :P
đ§ When insulin does change â itâs about diet, not just body fat
Carter et al. (2009, AJVR 70:125â132)
When horses were fed double their energy needs on a sweet feed that was over 30 % sugar + starch, they put on about 20 % body weight and their insulin sensitivity dropped.
â The issue wasnât âbeing fatâ â it was the high-starch diet driving the change.
Silva et al. (2020, Pesq Vet Bras 40:1â9)
Horses on a grain-heavy, high-calorie ration showed insulin dysregulation after 3 months â then went back to normal once their metabolism caught up, even though they were still obese.
â Again, the problem was what they were eating, not just how big they got.
đŸ When insulin doesnât change â even with weight gain
Bamford et al. (2016, EVJ 48:368â373)
Horses and ponies fed a high-fat, low-glycaemic diet for 20 weeks became properly round (BCS â„ 7) but stayed insulin-sensitive.
LindĂ„se et al. (2016, AJVR 77:300â309)
On a forage-plus-fat diet fed at 2œ Ă maintenance, insulin sensitivity didnât budge during weight gain â and improved by more than 50 % once they went onto pasture.
Nostell et al. (2020, EVJ 52:368â373)
Obese mares (BCS > 7) on haylage + fat kept normal insulin sensitivity but had higher blood pressure and cortisol. So obesity affected circulation, not metabolism.
Blaue et al. (2019, Dom Anim Endocrinol 69:1â11)
After one to two years of moderate-starch overfeeding, most ponies and horses stayed metabolically normal. Only three developed insulin dysregulation â and laminitis showed up only in those individuals.
âïž The takeaway
Across all these studies, insulin issues showed up only when diets were high in sugar and starch.
Feeding more calories from fat or forage made horses fatter, sure â but didnât make them insulin-resistant.
And laminitis occurred only when true insulin dysregulation developed, not simply because the horse was overweight.
đ So far, research hasnât found a causal link between âbeing fatâ and insulin resistance or laminitis â itâs the diet composition that matters most.