LEMP Rottweilers Australia

03/10/2020

https://m.youtube.com/watch?feature=share&v=cWaVcXpfypE

This video is about the progression, treatments and subsequent improvements in a Rottweiler with Leukoencephalomyelopathy (LEMP). LEMP is a rare juvenile-ons...

10/08/2020

I would like to let it be known that I myself have had a litter not long ago where I have tested 4 of the 6 puppies so far and have produced 3 x LEMP CARRIERS with only one being CLEAR of the LEMP disease!
All of my dogs have been tested and are all clear of LEMP so please people when choosing to breed your Rottweilers make sure that you check that both parents have been tested for LEMP and make sure they are at the least not both carriers.
It’s all we can do to avoid having affected pups born for the sake of the health of the pups.
Please don’t take this lightly it is here in Australia for sure!

27/07/2020

Rottweilers & Great Danes

LEMP in Rottweilers is a autosomal recessive central neverous system disease resulting from a 1 basepair insertion within the LEMP gene; cincal signs may develop as early as 1 year of age. All studied Rottweilers homozygous affected (D/D) for this LEMP mutation have shown clinical signs of disease. However, not all Rottweilers with suspected LEMP have tested affected for this mutation. It is possible that these dogs may be suffering from a different form of LEMP or the other neurodegenerative diseases described in this breed, including - Neuroaxonal Dystropy (NAD).

Population testing of >200 Rottweilers indicates that the carrier rate of this mutation is ~8%.
Although no affected Great Danes have yet been observed, population testing of >250 Great Danes indicates that the carrier rate of this mutation is ~8%.

27/07/2020

Leukoencephalomyelopathy (LEMP)

A neurological disorder, termed leukoencephalomyelopathy (LEMP) has described in Rottweiler and Leonberger dogs. LEMP is a recessively inherited neurodegenerative disorder that affects the white matter of the central nervous system (CNS). Canine LEMP is characterized by slowly worsening gait abnormalities, especially spontaneous knuckling, dragging of the paws and hypermetria of the thoracic limbs, and a characteristic pattern on magnetic resonance imaging (MRI). Affected dogs show corresponding gross lesions in the cervical spinal cord white matter that may extend to the thoracic spinal cord, as well as to the brain; peripheral nerve and muscle biopsies are unremarkable. Canine LEMP often shows a juvenile onset and is characterized by a generalized progressive ataxia. Spinal reflexes of affected dogs are mostly normal. In the progressive clinical course of the disease, affected dogs may become increasingly immobile within a few months. Like many diseases of the CNS, there is no effective treatment for LEMP. Since in most cases the dog is not in pain, but is strongly restricted in its quality of life, owners are encouraged to ask a veterinarian for advice.

27/07/2020

https://orivet.com/store/breed-list?species=canine&breed=Rottweiler

Genetic Testing for animals include Canine DNA Testing & Feline DNA Testing (dog dna test , cat dna test) | Canine Diseases & Canine Traits (Dog Diseases & Dog Traits) | Feline Diseases

27/07/2020

27/07/2020

27/07/2020

LEMP affected dog diagnosed via DNA thanks to George from Orivet for testing this boy!

I have posted each video separate please look at each one and let’s try and get rid of this disease from Australia by making sure that when you are looking at purchasing a Rottweiler from anybody please ask to see the original full DNA test results for JLPP and LEMP as these are very similar JLPP is much more severe as the puppy won’t live as long!

But they are still avoidable if the parents are tested and clear!

This boy has just been put to sleep at such a young age,
it’s so sad!

07/07/2020

I would like to help get the word out about this disease!

There are carriers in Australia as there have been proven cases of affected dogs.

I am hoping that putting this out there it will bring attention for breeders and puppy buyers to ask the question “have the parents been tested for LEMP? If so can we see copies of the paperworkshowing results?”

Let’s try and get on top of this before it is disregarded for so long like the JLPP was and there were so many carriers been bred with carriers resulting in Affected puppies being sold to unsuspecting people.

https://www.orivet.com/store/canine-disease/leukoencephalomyelopathy-lemp---single-assay-test

https://vgl.ucdavis.edu/test/lemp

Leukoencephalomyelopathy is a neurodegenerative disorder of the central nervous system characterized by a generalized, progressive loss of balance with increasing immobility.