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Paws and Claws Pet Care Services We are a team of experienced professionals ready to provide quality veterinary care to our furry fri

08/05/2021
21/01/2021

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PANDORA SYNDROME IN CATS❗❗The term “Pandora syndrome” is based on 4 decades of research and clinical experience with cat...
18/01/2021

PANDORA SYNDROME IN CATS❗❗

The term “Pandora syndrome” is based on 4 decades of research and clinical experience with cats with chronic lower urinary tract (LUT) signs (i.e., hematuria, pollakiuria, periuria, and stranguria). Studying LUT signs in cats, they were referred to as “feline urological syndrome” (FUS) or “feline lower urinary tract disease” (FLUTD) and were thought to result from consumption of an improperly formulated diet that contained too much magnesium and that resulted in a urinary pH that promoted formation of a magnesium-ammonium-phosphate (struvite) stone, which was the proximate cause of the LUT signs. It has turned out that nearly all of this explanation was wrong. Struvite urolithiasis was found not to be the most common cause of chronic LUT signs; rather, reducing the magnesium and urine pH (primarily by adding acid to the diet) only succeeded in a shift from the most prevalent stone type being struvite to about half of stone diagnoses being calcium oxalate, and cats continued to suffer from chronic LUT signs without any stone present at all.

Pandora syndrome is an “anxiopathy”: that is, a pathologic condition resulting from chronic activation of the central stress response system (CSRS). Persistent activation of this system by a chronic perception of threat that exceeds the animal’s perception of control mobilizes activity in variable combinations of the autonomic nervous, endocrine, and immune systems. The result can be pathology affecting any organ system or combination of organ systems.

The variability in response to chronic perception of threat may result from organ-specific differences in familial (genetic, epigenetic, environmental) vulnerability and from exposure to threatening events such that the CSRS is durably sensitized to the environment. Such events often occur early in life, even before birth when the CSRS is most plastic and vulnerable to the events communicated to it by the mother through the placenta. However, the CSRS can be sensitized by sufficiently harsh events at any time of life.

DIAGNOSING PANDORA SYNDROME
Many organ systems are represented in expression of Pandora syndrome
Pandora syndrome is only one possible cause of the disorders listed and may or may not be eventually added to the differential diagnostic criteria for that disorder.
A tentative diagnosis of Pandora syndrome rests primarily on the results of a comprehensive history and physical examination. Evaluation of the quality of resources for safe space; food and water availability, location, and management; litter box hygiene, opportunities for activity, play, and social contact can also be helpful.
Decisions about medical care of cats with Pandora syndrome depend on the specific presenting problem
Regards
Dr Faizan Asghar (DVM , RVMP)
03038183132

Celebrate World Animal Day - 4 October👋MISSION: TO RAISE THE STATUS OF ANIMALS IN ORDER TO IMPROVE WELFARE STANDARDS ARO...
04/10/2020

Celebrate World Animal Day - 4 October

👋MISSION: TO RAISE THE STATUS OF ANIMALS IN ORDER TO IMPROVE WELFARE STANDARDS AROUND THE GLOBE
👏🏾Building the celebration of World Animal Day mobilises people for action now for a better future for animals.

Your animal not doing well ?? We are available 24/7 to provide quality veterinary care to your animal at your door stepR...
15/07/2020

Your animal not doing well ??
We are available 24/7 to provide quality veterinary care to your animal at your door step
Regards
Dr Faizan Asghar (DVM) (UAF)
0303-8183132

21/06/2020
14/05/2020
Parvovirus is a highly infectious disease of dogs that can be fatal. It is also known as canine parvovirus, or CPV.Many ...
14/05/2020

Parvovirus is a highly infectious disease of dogs that can be fatal. It is also known as canine parvovirus, or CPV.Many dogs who are diagnosed with parvo will die.

The virus attacks cells in a dog’s intestines and stops them from being able to absorb vital nutrients. This means that a dog or puppy will become very weak and dehydrated.

Young puppies and unvaccinated dogs are most at risk from becoming victims of parvo. Youngsters between six weeks and six months old are also more susceptible to secondary infections, or they may die from dehydration.

Symptoms:

Symptoms of parvo include foul-smelling diarrhoea with blood in it, vomiting, loss of appetite, collapse, depression, fever and sudden death

Transmission:

Parvo is highly contagious to other dogs and spreads very easily around dogs and puppies that aren’t up to date with their vaccinations.

It takes up to seven days for a dog to show signs of having parvovirus after they have caught it.

Parvovirus spreads through body fluids, including in a dog’s poo and vomit. It is extremely hardy and can survive in the environment outside the body – for example in the grass at a park – for at least six months, and possibly much longer. Your dog can even contract parvo by sniffing another dog’s poo and it’s not uncommon for dogs to catch parvo when out for a walk.

If your dog has come into contact with bedding, food and water bowls, carpet, or a kennel that a dog with parvovirus has touched, they can catch the virus. Parvo can also be spread on shoes, clothing and human hands.

Prevention:

Vaccination is the best way to prevent the disease .A puppy should have their first vaccine at five weeks old. They will then need a second vaccine three weeks later. After that, they will need a booster vaccine at one year old and then annual booster dose once every year.
Regards
Paws & Claws pet care
03038183132

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