 
                                                                                                    16/10/2025
                                            𝙏𝙝𝙚 𝙋𝙤𝙬𝙚𝙧 𝙤𝙛 𝙩𝙝𝙚 𝙋𝙞𝙩𝙪𝙞𝙩𝙖𝙧𝙮 𝙂𝙡𝙖𝙣𝙙
Located at the base of the horse’s brain is a pea-sized organ called the pituitary gland. Specialized cells in this organ produce proteins and peptides, which the pituitary gland then sends throughout the body to perform a variety of specialized functions. One of the proteins secreted by the pituitary gland is called growth hormone. 
While it was once believed that growth hormone was only necessary during growth and developmental stages, research has shown that it plays a vital role throughout the horse’s lifespan. Without optimal growth hormone levels, horses experience a reduced ability to repair and regenerate cells. They may perform below their peak capabilities, be predisposed to injury, age prematurely, or even die at a younger age.
When released into the circulation, growth hormone acts directly on cells to stimulate regeneration and repair, and in liver cells specifically, it triggers the release of Insulin-like growth factor 1 (IGF-1). Whereas growth hormone only has a half-life of 20 minutes, IGF-1 has a half-life of 22 hours! Together, growth hormone and IGF-1 work as a signaling protein to prompt around-the-clock growth in young cells, and regeneration and repair in stressed or damaged cells. A deficiency in growth hormone leads to a deficiency in IGF-1, which in turn creates a reduced ability to repair and regenerate cells.
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