26/06/2023
Interesting
REASONS I LOVE SEAWEED #147: MAY LOWER URIC ACID AND HYPERTENSION
Had a question from a Dalmatian owner re the purine content of Canident. I don't know. Never thought to check. Looking into it now. But look what I'm after finding on that note...
Purines are a type of protein that is converted by enzymes in the body first to uric acid and finally allantoin which is highly soluble and easily excreted from the body. Easy pee-sy,
Most Dalmatians, however, lack the enzymatic ability to convert uric acid into allantoin, a compound that is easily excreted by the kidneys.
The net result is most Dallies are HUA, meaning high in uric acid.
The problem is as uric acid builds it can result in urate crystals and stones.
Ouch.
So Dallie owners (rightly) obsess about purine contents and aim to keep them low to keep uric acid low.
It happens that most purine content info actually arises from the gout realm as HUA is a significant risk factor for this painful disease of humans (sort of like bad arthritis with lots of red swelling).
Interestingly, I just found on a gout website that seaweed consumption has been found to REDUCE uric acid content of at least human men (REF 1).
How exactly is a bit beyond me on such a warm, sunny day, but for the nerds that need it:
"Previous studies have suggested that seaweed antioxidants significantly reduced xanthine oxidase activity and expression in liver, as well as decreased urate-anion transporter 1 expression, increased organic anion transporter 1 and 3 expressions, and thus inhibited the uric acid production and reabsorption and enhanced urate secretion".
Studies show HUA is also a serious risk factor for cardiovascular events and hypertension...and studies show seaweed can help there too (REF 2, 3).
Bloody hell Conor, this is amazing, where can we get this sea-weed you speak of?
From the sea, guys. Go down to the local shore as the tide goes out (away from any ports or marinas...). Snip some brown stuff off a rock. Hang in your garage until it dries and feed you and your dog 1-2g of dried brown seaweed per day to reap many of the benefits above as well as getting an unbelievable nutrient boost to your diet.
But it's hot and I'm not arsed going down the beach and doing that, I hear you say!
Perfect, because we are fully stocked here with a range of amazing seaweed-based products.
Of all, I recommend Canident. Not only might you get the benefits above but it WILL clean their teeth in 5-8wks or your money back. You can keep the product (and the nutrient boost, and reduction in hypertension and HUA).
https://dogsfirst.ie/product/canident-2/
REFERENCES
REF 1 Zhang, T., Wang, Y., Gu, Y., Meng, G., Zhang, Q., Liu, L., Wu, H., Zhang, S., Wang, X., Sun, S., Wang, X., Zhou, M., Jiao, H., Jia, Q., Song, K., Wu, Y., Wu, X. H., & Niu, K. (2021). Title: Relationship between seaweeds consumption and hyperuricemia in general adults: A Population-based Study from the TCLSIH Cohort Study. The British journal of nutrition, 1–31. Advance online publication.
REF 2 Teas, J. et al. Could dietary seaweed reverse the metabolic syndrome? 145–157
REF 3 du Preez, R. et al. Carrageenans from the Red Seaweed Sarconema filiforme Attenuate Symptoms of Diet-Induced Metabolic Syndrome in Rats.