26/07/2024
Since about a dozen people have asked about Shield4Pets, I am posting the article that I share with those who ask.
WHAT IS SHIELD4PETS, A FERMENTED
WHEAT GERM SUPPLEMENT FOR PETS?
Shield4Pets is derived from the germ (endosperm, or seed) of the wheat plant and is a by-product of milling wheat kernels to produce flour. This plant portion is hypoallergenic, gluten-free, and not linked to allergies.
It differs from ordinary wheat germ in that it is fermented to concentrate the substituted benzo-quinones, which are biologically active. Concentration allows the immunomodulatory effects of the substituted benzoquinones to be obtained without consuming impractically large amounts of wheat germ. The fermented wheat germ product is treated with ionizing energy to reach the appropriate microbiological purity. Shield4Pets is manufactured by Biropharma Animal Health in Budapest, Hungary, from non-GMO sources.
The finished product is rich in macro- and microelements, vitamins, and unsaturated fatty acids. Its essential components include herbal benzoic- and hydroquinones with immune-modulating and antimicrobial effects. Shield4Pets is manufactured using the same technology as the FDA-approved human supplement. During the production of the active substances, the two production lines separate during the solidification or drying steps. Shield4Pets contains the water-soluble part AND the solid parts as well. It is sold as a feeding material for animals of all sizes. If we look only at the raw production method, then Shield4Pets contains more types of functional molecules than any other product. This tells us a lot about the ingredients.
How does Shield4Pets work?
In short, Shield4Pets helps in immune system defenses. The product has a complex biological effect affecting the humoral and cellular immune systems. The NK cell is like a cop that stops someone suspicious, demands to see an ID, and asks a few questions. If it decides the target cell is “innocent,” it moves on. If not, watch out! Any invading or mutated cell can only grow and thrive if it convinces the body’s NK “police” that it’s a normal cell. Unfortunately, that’s exactly what cancer cells do.
Cancer “lies” to the NK cells, telling the NK’s receptors, “It’s okay, I’m a good guy.” It does this with a surface molecule called MHC-1 that performs the same function as a criminal’s fake ID. Once the NK cell “reads” this molecule, it moves on.
But here’s where Fermented Wheat Germ comes in. Fermented Wheat Germ suppresses the cancer cell’s ability to display the “fake ID” and thereby lie to NK cells. The immune system can now consume the invader and keep it from growing and multiplying. (Okay, an honest cop doesn’t devour a criminal, so the metaphor breaks down here. But on the whole, I’m glad these NK cops are killers! After all, that’s why they’re called natural killer cells.) There are numerous published findings on successful human clinical trials of Fermented Wheat Germ, with more underway.
The mutated genes in cancer cells constantly urge these malignant cells to divide. To maintain the processes of rapid cell division, the cell metabolism must also be changed; the cell needs to adapt nucleic acids (RNA/DNA) and other constituents for its use. Cancer cells adapt their metabolism to gain energy, enabling them to utilize glucose's most abundant resource in circulation. This is why so many cancer diets are based on no carbohydrates or sugars. To maintain a continuous proliferation, glucose must be utilized continuously for synthetic (anabolic) biochemical processes.
Tumor cells quickly adapt to this glucose-based metabolism and can take up and use enormous quantities of this molecule - up to 20-30 times more than normal cells. Cancer cells use one part of glucose for energy production and another for synthesizing nucleic acids, which are the building blocks of RNA and DNA. Quite a brilliant little system these cancer cells have! This constant glucose flow to cancer cells is one of the reasons cancer patients have no energy and no appetite.
Shield4Pets works by decreasing the glucose uptake of tumor cells dose-dependently and inhibiting the production of ribose and deoxyribose to make a complex group of processes simple for laypeople. This sugar is the backbone of DNA. It also inhibits key enzymes that cancer cells need to grow. Further, Fermented Wheat Germ enhances TNFalpha (tumor necrosis factor-alpha) production, inhibiting tumor angiogenesis. Angiogenesis is the ability of cancer cells to keep themselves well-supplied with blood. It produces an enzyme that tells the circulatory system to increase circulation or blood supply.
Much research in the States has been focused on anti-angiogenesis, but Shield4Pets works on many fronts, making it a powerful weapon. Think of cancer as an evil entity that circumvents the natural processes in the body to establish an evil empire that builds itself into a monster! Shield4Pets deconstructs cancer cells by working in many of these processes, turning them back into what they were before the onslaught of cancer, which took control and cleverly used these natural processes to grow itself at an enormous rate.
Shield4Pets also has an immune-modulating effect by selectively inhibiting MHC-I (major histocompatibility-I) expression on the surface of tumor cells. It can restore the immune system to its pre-damaged condition by re-teaching T cells proper cell recognition. The MHC genes regulate antibody recognition, meaning Shield4Pets is also extremely useful in autoimmune diseases.
How is it used?
This immune-modulating ability makes it very useful for many other treatments. We are still discovering how it works on various body systems, but so far, it is used to assist in treating immune and autoimmune diseases, skin tags, and benign and malignant tumors. One tiny little Pomeranian responded to the supplement by re-growing a full coat after years of suffering from alopecia! Really.
The human form of fermented wheat germ extract has been studied with mice …”The down-regulation of auto-antibody production following treatment with FWGE was observed in a mouse model for systemic lupus erythematosus (SLE), indicating that FWGE can facilitate the clinical manifestation of experimental SLE.”
One of the most exciting studies showing the value of this supplement was published in March 2018. It's long but well worth reading if you own horses or any other animal;
https://immunovet.co/.../fwge-immunovet-for-horses-a-6.../
In skin diseases, the efficiency of the therapy of various infectious skin diseases, allergic skin inflammation, and increased wound healing can be improved by helping stop the licking of itchy skin.
It benefits patients with painful arthritis and can be safely combined with all anti-inflammatory treatments. Overall improvement in physical condition and quality of life are noticeable after short-term use, and recovery is speeded up after surgical procedures. This is especially true with senior animals. They have an increased appetite, improved mobility, and a greater sense of well-being, making them more responsive and active. It is as if this supplement is some form of elixir for older pets.
Side Effects
How can one supplement accomplish all of these things? Studies done with humans show how well it works. You can Google Fermented Wheat Germ Extract or input the phrase into the National Library of Medicine online search:
https://pubmed.ncbi.nlm.nih.gov/?term=fermented+wheat+germ+extract
The only known side effect can be a soft stool, but it is seen infrequently. No other known other side effects have been noted. Adding a probiotic to the food will resolve this issue.
Known Interactions
It is used with all forms of chemotherapy and has been proven to extend survival time and quality of life in human patients without any side effects except a loose stool. It should not be taken at the same time as vitamin C (allow a 2-hour window on either side of Shield4Pets). Otherwise, there are no restrictions. Adding Omega 3 essential fatty acids in fish oil, preferably from wild-caught fish, will enhance this product.
Important Warnings
Using Shield4Pets is not a substitute for clinical oncology treatment and medications. This product should be kept strictly out of the reach of children!
Dosage and Usage of Shield4Pets Powder
As an adjunct to cancer treatments, the dose is 2 grams for every 25 pounds of body weight. You can double that amount to achieve a better immune system balance.
As an overall health supplement, sprinkle 4 grams or one teaspoon daily on food or mix with cooked or raw food.
Grains are Off Limits!
The word “wheat” induces a very negative response in most people with pets. Understandably, that is why we wish to explain that fermented wheat germ is no longer a grain, wheat. During the patented manufacturing process, a new set of compounds is created with a quality different from the starting materials. The biological effects of this product are most unique. Fermented Wheat Germ has been extensively studied for its anti-cancer and immuno-modulating effects. The first studies were carried out in the middle of the 1990s. Since then, Fermented Wheat Germ has become one of the most comprehensively studied complex products with an active ingredient of plant origin.
Due to its complex nature, Fermented Wheat Germ Extract contains numerous additional molecules besides its main ingredient. Many of them, like fructose, are used as a catalyst to begin the fermentation progress and are necessary. Other ingredients in the tablet formula are also required to keep the tablet together and to help it dissolve, plus natural beef flavoring from Poland.
So why are there no studies to validate fermented wheat germ for pets?
To the company that created and sells this supplement, Biropharma, in Hungary, the feeding material is a secondary product, but no funding is available to substantiate any claims. Using this since it was released in 2008 for sale to pets, we are compiling the information. We work with veterinarians to gather their results and combine that with feedback from people using it. We hope to present the information to the American Veterinary Holistic Medical Foundation to gain their interest in funding actual studies. You will become part of future studies if you share your results.
Meanwhile, the fermented wheat germ people use is FDA-approved for that species. Still, since nutrients, nutraceuticals, and supplements are not in the FDA’s vocabulary for animals, they do not allow their import as a supplement. It is either a food or a drug. Drugs are destroyed in customs; food can be allowed, so we import this as food.
It is easy to use as a powder on food or as a flavored chewable tablet. In the United States and Canada, it is sold at www.Shield4Pets.com
© 2024 Bouyet