30/07/2024
‼️ The FDA is alerting pet owners and veterinarians of the potential for neurologic adverse events in dogs and cats when treated with drugs that are in the isoxazoline class.
The FDA-approved drugs in this class are:
Bravecto (fluralaner) tablets for dogs
Bravecto (fluralaner) topical solution for cats and dogs
Bravecto Plus (fluralaner and moxidectin) topical solution for cats
Bravecto 1-month (fluralaner) tablets for dogs
Credelio (lotilaner) tablets for dogs and cats
Nexgard (afoxolaner) tablets for dogs
Nexgard Plus (afoxolaner, moxidectin, and pyrantel) chewable tablets for dogs
Nexgard Combo (esafoxolaner, eprinomectin, and praziquantel) topical solution for cats
Simparica (sarolaner) tablets for dogs
Simparica Trio (sarolaner, moxidectin and pyrantel) tablets for dogs
Revolution Plus (selamectin and sarolaner) topical solution for cats
Source:
https://www.fda.gov/animal-veterinary/animal-health-literacy/fact-sheet-pet-owners-and-veterinarians-about-potential-adverse-events-associated-isoxazoline-flea
Let´s have a look at BRAVECTO directly from the webside of the producer Merck & Co., Inc.:
"Bravecto is safe to use and efficacious in adult dogs and puppies over 6 months of age" - this means NOT for very young puppies!!!
SIDE EFFECTS of one of those products:
"BRAVECTO PLUS (fluralaner and moxidectin topical solution) for Cats: The most commonly reported adverse reactions include vomiting, hair loss, itching, diarrhea, lethargy, dry skin, elevated ALT, and hypersalivation...
All BRAVECTO products contain fluralaner, which is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Neurologic adverse reactions have been reported in cats receiving isoxazoline class drugs, even in cats without a history of neurologic disorders. Use with caution in cats with a history of neurologic disorders. "
Source:
https://www.merck-animal-health-usa.com/bravecto/fleas-ticks-12-week-treatment #:~:text=BRAVECTO%201%2DMONTH%20(fluralaner),%2C%20lethargy%2C%20and%20weight%20loss.
Other expample - Advantix spot on side effects on dogs:
Side Effects:
"Monitor your dog after application. Side effects, although very rare, may include signs of skin irritation such as redness, scratching, or other signs of discomfort. Gastrointestinal signs such as vomiting or diarrhea have also been reported. If these or other side effects (such as lethargy or agitation) occur, consult your veterinarian"
Source:
https://www3.epa.gov/pesticides/chem_search/ppls/011556-00141-20131119.pdf
"Symptoms of K9 Advantix Allergies in Dogs
If your dog is having a reaction from K9 Advantix or K9 Advantix II, the symptoms may vary depending on your dog’s coat, size, and breed. K9 Advantix should not be used on dogs that weigh less than four pounds. Symptoms of an allergic reaction to this product may include:
Sensitivity at the application site
Skin irritation
Scratching the skin
Discomfort
Redness
Gastrointestinal discomfort
Lethargy
Causes of K9 Advantix Allergies in Dogs
Causes of K9 Advantix allergic reactions begin with the application of the product onto your dog’s skin. Specific causes include:
Oversensitive immune system
The increased production of antibodies to fight the allergen
Immune system identifies the solution as being harmful to the body
In this process, chemicals are released to cause the reactions
Diagnosis of K9 Advantix Allergies in Dogs
If you suspect your dog is having an allergic reaction to K9 Advantix or K9 Advantix II, it is important to make an appointment with your veterinarian. Once you take your dog to the veterinarian, the medical professional will assess your dog’s symptoms. Your dog may show a variety of symptoms, and the severity may vary depending on the allergic reaction of your companion.
The veterinarian will ask you questions pertaining to everything “new” you have introduced into your dog’s life. He may ask you about various foods, allergens within the home, or anything that you have recently applied to your dog. With those questions, you may come to the conclusion that you recently applied the flea and tick treatment."
Source:
https://wagwalking.com/condition/k9-advantix
For more information, feel free to google :-)
K9 Advantix allergies in dogs occur when dogs are exposed to the chemicals within K9 Advantix or K9 Advantix II. The chemicals within the products cause an adverse reaction within the dog’s body, which is marked by a variety of symptoms.
