03/09/2025
~ It's WeedsDay! ~
Let's look at our FrIDay toxic plant and ID quiz from last week. We didn't have a correct ID, surprisingly.
They are locow**ds (Astragalus and Oxytropis spp.) and they have a strong potential for toxicity in equines.
Locow**d is a general term that also includes the milkvetches. There are over twenty known toxic locow**d and closely related milkvetch species (though thankfully the majority of these species are not known to be toxic), and they vary from region to region. The Astragalus spp. are considered to be higher in toxicity than the Oxytropis spp.
They can cause toxic events in all grazing animals, though there is great variability, depending upon each animal's age/size/condition, the amount eaten, and the length of time it was consumed. The main toxic compound in locow**ds is swainsonine, an alkaloid, though a few also contain a neurotoxin. We see most toxicity from these plants in the Plains and Rocky Mountain states of the US.
The toxic threshold is often substantial, meaning that the quantity that must be ingested to induce toxicity is fairly large. An exact amount has not yet been established. In pastures with only a small population of locow**d, ingestion of enough to reach the threshold is unlikely.
However, in infested pastures with low populations of good grasses, given that equines are especially susceptible and may develop picas that induce them to seek out the plant, the chance of toxic events is much higher. Studies show that toxicity normally occurs after several days to weeks of grazing on the plants, though it may infrequently occur rapidly.
(As a FYI: it is an endophytic fungus that produces swainsonine in locow**ds, not the plant itself. Therefore, the amount of toxin depends upon the fungal level, growing conditions, growth stage, and species of locow**d. It appears that the most palatable stage occurs during and after flowering, before seed pods mature.)
Some symptoms of toxicity include tremors, reduced water intake, decreased appetite and weight loss, anxiety, odd mouth movements, rough/dull coat, unpredictable behavior, lack of coordination reluctance to move, spontaneous abortion, depression, cardiac events, and death.
Locoism tends to be permanent in equines with severe toxicity. Even in more mild cases, odd behaviors take months to abate. Animals that recover often exhibit a preference for locow**ds and will seek them out when returned to pasture.
There is also a concern about locow**ds causing selenium toxicity (chronic selenosis). Some species of Astragalus are accumulators (mostly milkvetches), but the amount of selenium in these plants would render them highly unpalatable, and thus very unlikely to be eaten. It takes selenium-rich soils for plants to bind toxic amounts of selenium; these are normally in areas of low rainfall. Plants will also accumulate more selenium during drought periods.
We cover clinical signs of Se toxicity in the 8/24 info-letter.
The first step after identifying locow**d or milkvetch as the source of toxicity is immediate removal of equines from the pasture or removal of suspected hay. Animals should be kept in a quiet and stress-free environment with good feed and clean water. Our vets will decide on treatment based on clinical signs, tests, and severity of toxicity.
Though hand-pulling is an option for removing just a few of these plants from pastures, control of locow**ds and vetches may be most successful with the use of herbicides. Specific recommendations may vary based on our location. Application is most effective from early bloom stage on, through fall. These are best used with the advice of our local w**d board, extension agent, or conservation district.
The seed bank is large for these plants, and the seeds remain viable for decades, so continued monitoring is a necessity, with the possible need for re-treatment. There are natural insect predators of locow**ds, so overuse of insecticides is not recommended in those areas.
Those species that have been most often associated with locoism include:
Astragalus emoryanus, emory milkvetch
A. lentigenosus, spotted loco, freckled milkvetch
A. mollissimus, woolly loco
A. missouriensis, Missouri milkvetch
A. nothoxys, sheep milkvetch
A. pubentissimus, Green River milkvetch
A. wootonii, Wooton loco
Oxytropis besseyi, Bessey's loco
O. campestris, field loco
O. lambertii, Lambert's loco
O. sericea, white loco
Our first step is to identify the species we have and whether it may be a problem plant. Identification of locow**ds and milkvetches can be difficult; we may have to enlist the help of someone who is knowledgeable in plant ID.
While it is necessary to remain vigilant about what is in our pastures, particularly with plants that induce picas, the foremost and best thing we can do to prevent toxic events is to ensure healthy populations of forage grasses through good pasture management practices and provide plentiful clean water.