09/12/2025
Pixie originally came to WAVES Dermatology for recurrent ear infections and persistent crusting on his ear pinnae that had been refractory to treatments. Apart from the skin lesions, Pixie was also unwell in himself.
Dr Amelia performed cytology from the crusting lesions and found acantholytic keratinocyte cells, raising concerns for an immune-mediated skin disorder: pemphigus foliaceus.
Dr Amelia performed biopsies and confirmed this diagnosis as well as identified an antibiotic resistant methicillin-resistant Staphylococcus aureus (MRSA) bacterial infection.
Pemphigus foliaceus is the most common autoimmune skin disease in cats. Early diagnosis is key, and many cats respond beautifully once immunomodulatory therapy is started.
In some cases, this condition can even be triggered by an adverse drug reaction, which is why a thorough history is essential.
Pixie is now feeling much better and looking happier! Dr Amelia will next try to taper the medications to ensure Pixie remains in remission.