Peak Pawformance

Peak Pawformance Peak Pawformance Canine Therapy specialises in myotherapy to ease muscle pain and restore muscle fun

Peak Pawformance Canine Therapy specialises in myotherapy to ease muscle pain and restore muscle function. It assesses for muscle weakness, muscle spasm or compensatory issues and work on the appropriate muscles to reduce areas of stress, and pain.

Canine Osteoarthritis awareness month! 🐾
14/05/2025

Canine Osteoarthritis awareness month! 🐾

Worth a read if you have a dog on this medication.
11/05/2025

Worth a read if you have a dog on this medication.

LIBRELA TRAGEDY
Can't stop thinking about the results of that Librela study by Farrell et al. (2025), published yesterday.

Ligament/tendon injury, polyarthritis, fracture, musculoskeletal neoplasia (new bone growth) and septic arthritis were reported NINE TIMES more frequently in Librela-treated dogs than the combined total of dogs treated with the comparator drugs for osteoarthritis.

Again, 9 times more than all the other drugs combined.

The 18-member expert panel unanimously concluded a strong suspicion of a causal association between Librela and accelerated joint destruction.

Many, like vet Josie Beug, have been warning us for a year to pay heed to the fact Librela managed to accumulate many times more adverse event reports since its release in the US in Oct 2023 (12,234 serious adverse event reports in just 18mths in America alone) than its nearest competitor, Rimadyl has EVER.

Bedinvetmab (Librela) was unleashed on the US pet market in October 2023 with an enormous budget from Zoetis and two small (highly questionable) studies (conducted by them). And that's all it took for, it seems, the worlds vets to start recommending it.

Because that's how it works, isn't it? A brand new, patented drug, shat out by the industry, accompanied by two little studies (run by them) and off we go to the races.

The first study, a safety and tolerance study, looked at varying doses of Librela (1mg/kg, 5mg/kg, 10mg/kg) in young, healthy, intact dogs aged 11-12 months. There was just 8 dogs in each group. After 6mths they did neurological tests, checked their vitals and that was that.

See, the manufacturers tested their drugs on young, robust dogs with no joint issues.

Farrell et al. (2025) were looking at side effects in older dogs with joint disease.

And they can do that little trial as often as they like AND they don't have to publish all the negative ones.

This was followed by, if you can believe it, a 6-month in-field study of 89 client-owned dogs WHO HAD PREVIOUSLY DEMONSTRATED A POSITIVE RESPONSE TO LIBRELA. After 6mths, the few adverse events noted were within predicted norms.

Veterinary Evidence took a look at these couple of studies prior to Librela's launch and concluded the supporting evidence was "weak", that any decision to use bedinvetmab "remains dependent on the judgement and experience of the clinician".
https://veterinaryevidence. org/index.php/ve/article/download/598/903?

See that? The onus is shifted to the clinician.

Do you know why? Because time and time again, once enough money is paid to the right people, dangerous drugs WILL get to market in the full knowledge that our doctors appear completely unable to notice / track side effects from the medications they are recommending.

Much like the absolute explosion in adverse events reported to VAERS following the introduction of mRNA gene therapies into the population five years ago, it's literally incredible how clinicians today will consistently ignore any and all adverse event reporting systems that we have put in place to FLAG ISSUES (since the Thalidomide scandal) until someone else tells them to stop.

Why is that?

In 2021, there was 717,577 adverse event reports submitted to VAERS for all COVID-19 vaccines combiines (nearly 300 million were administered to Americans that year), when typically VAERS receives between 30,000 and 50,000 adverse event reports annually for all other vaccines combined (150 million administered in the US in a given year).

And remember, studies show the figures that are reported to adverse event reporting systems are approximately 1-5% of the ACTUAL events that are going on.

So, for context, that 12,000 adverse events for librela in just 18mths in the US would become 240,000.

Folk say, but 25 million doses were given!! Yes, GLOBALLY. If we guess that maybe half those were sold in the US, it means potential ruin for a dog every 1 in 50 doses. Dogs are taking it monthly.

But worse, it was very predictable that this was going to happen. The drug couldn't pass human trials due to side effects.

Bedinvetmab, marketed as Librela, is a monoclonal antibody designed to alleviate osteoarthritis pain in dogs by targeting nerve growth factor (NGF).

While bedinvetmab itself was not developed for human use, its mechanism of action is similar-bordering-identical to other anti-NGF monoclonal antibodies (mAbs) that have been investigated in human clinical trials, namely tanezumab, fasinumab, and fulranumab.

Exactly like mRNA gene therapies before they were forced through in 2021, ALL trials for NGF monoclonal antibodies revealed major safety concerns that blocked their prior release, mostly concerning patients developing rapidly progressive osteoarthritis and accelerated joint degeneration. Even when adjusting the dose down and placing restrictions on concurrent NSAID use, the risks persisted. The US FDA had no other choice but to halt all trials of all anti-NGF monoclonal antibody treatments in 2012.

As folk will inevitably point out, there's no doubt Librela works for some, yes, the same way the mRNA gene therapies MAY have been useful in the initial stages for older, at-risk folk, maybe (although, side effects aside, studies show the more you took the more likely you were to get Covid...) but when you look at the data overall, its clear there is gong to be a lot of dogs very negatively impacted for life by this one.

At a minimum, please ask your vet for any other options in the osteo-arthritic pain relief department.

There are a plethora of things you can do to help osteoarthritis, the first is by reducing inflammation in the body. This means no more kibble as, studies show, it's inflammatory. Raw dog food is full of fresh calcium, glucosamine, chondroitin, hyaluronic acid, etc, all of which joints NEED. Moreover, the higher protein diets will reduce obesity, shown to greatly aggravate OA. You can jack up the omega 3, add some muscles. And this is all before you consider antiinflammatory, pain-relieving herbs like boswelia, devils claw. There is nutraceuticals. There is red light therapy. There is acupuncture. Massage. Hydro.

Has your vet done all of this with you before reaching for the NSAIDs and pain meds?

I doubt it. It's not vindictive. They know little about all those "alternative" (cheap, effective) treatments.

If you want some more options for osteoarthritis pain, askbradi .com.

If you feel you have been harmed, you can fill in the adverse event report yourself, doesn't need a vet.

UK folk here www. gov. uk/report-veterinary-medicine-problem

US folk here www. fda. gov/animal-veterinary/report-problem/how-report-animal-drug-side-effects-and-product-problems

REF
www.frontiersin. org/journals/veterinary-science/articles/10.3389/fvets.2025.1581490/full

02/05/2025

Dogs possess remarkable sensory abilities that allow them to perceive things beyond human detection, often leading to behaviors that seem paranormal. For example, they can sense subtle environmental changes, like the pressure drop before a storm, due to their acute hearing and sensitivity to vibrations.

Dogs are also thought to detect seismic activity, such as earthquakes, before humans feel them. Their ability to sense low-frequency vibrations or changes in the Earth's magnetic field may explain this behavior, though scientific evidence is still inconclusive.

Another remarkable ability dogs have is detecting illnesses in humans. Their sense of smell is so refined that they can identify changes in a person’s body chemistry, such as fluctuations in blood sugar or even the presence of cancer.

Dogs are highly attuned to human emotions, often sensing when their owners are upset or anxious. This emotional sensitivity sometimes leads them to exhibit behaviors like comforting or protecting their owners.

Lastly, dogs occasionally act strangely, staring at empty spaces or barking at nothing, which many attribute to their acute senses picking up stimuli beyond human perception.

26/04/2025

When you get your 8/10 week old puppies, please keep this image in mind. Their bones do not even touch yet. They plod around so cutely with big floppy paws and wobbly movement because their joints are entirely made up of muscle, tendons, ligaments with skin covering. Nothing is fitting tightly together or has a true socket yet.
When you run them excessively or don't restrict their exercise to stop them from overdoing it during this period you don't give them a chance to grow properly. Every big jump or excited bouncing run causes impacts between the bones. In reasonable amounts this is not problematic and is the normal wear and tear that every animal will engage in.
But when you're letting puppy jump up and down off the lounge or bed, take them for long walks/hikes, you are damaging that forming joint. When you let the puppy scramble on tile with no traction you are damaging the joint.
You only get the chance to grow them once. A well built body is something that comes from excellent breeding and a great upbringing-BOTH, not just one.
Once grown - around 12-18 months depending on their breed, you will have the rest of their life to spend playing and engaging in higher impact exercise. So keep it calm while they're still little baby puppies and give the gift that can only be given once.

This Xray is of a 2 week old puppy. Credit goes for respective owner.

26/04/2025

Recognising the Unseen Strength of Our Vets on World Vet Day

Our vets are more than just experts in animal health. They are the caregivers who show up with empathy, offering support and comfort at every step of a pet’s journey.
They carry the weight of difficult decisions and the emotional load that comes with helping families say goodbye to their beloved pets.

It’s important to recognise the mental and emotional toll that comes with this work, and today, we stand with and thank our vets for their extraordinary compassion, dedication, and resilience.

To all our vets, your hard work, your heart, and your strength make all the difference. 💙

21/04/2025

A new study published in the Cadillac of all journals, Nature, analyzed 32 dry & canned pet food products from the United States, (93 in total worldwide) and revealed a widespread presence of toxic metals, including chromium (Cr), mercury (Hg), & arsenic (As), across various brands. Notably, lead (Pb) levels were the highest overall, with some samples exceeding established regulatory safety limits.

Exposure to lead in dogs can have negative effects on the gastrointestinal tract, nervous system, cardiovascular system, and blood. Cadmium is known for its cumulative toxicity and can induce cancer in animals through various mechanisms, and exposure to it can cause nephrotoxicity and damage to the small intestine. These heavy metals found in pet food place added stress on key organs, especially the kidneys, which are responsible for filtering toxins from the body. Over time, that toxic burden can contribute to kidney dysfunction and disease. 😿

So what can you do?

One simple way to support detox is chlorella🦠— a green algae known for its ability to bind heavy metals in the gut and support gentle detoxification. It’s not a cure-all, but it can be a helpful part of your toolkit. (Be sure to use a clean, third-party tested brand.)

🌱Dosages:
Small pets (

Does as pets has been long known due to the benefit of the Human-Animal Interaction! 💕
20/02/2024

Does as pets has been long known due to the benefit of the Human-Animal Interaction! 💕

Mummy of a 3,500-year-old dog,
It was the little dog of Pharaoh Amenhotep from 1427 BC.

Found mummified with his necklace, a bowl of water and his own perfume bottle.

This mummy of a dog was found inside tomb KV50, known as the Tomb of the Animals, in the Valley of the Kings.

It is believed to be one of the pets of Pharaoh Amenhotep II, who ruled Ancient Egypt between 1427 and 1401 BC, due to the proximity of this tomb to that of the pharaoh.

22/01/2024

"If I die before my dog, let him see my body.
He understands death, if he feels my death he can cry for me.
If he doesn't see me again he will think I abandoned him and he will continue waiting for my return.
If I die before my companion, let him say goodbye to me.
"Dogs are an endless friendship, a loyal friend, a part of life and a reason to exist! "❤️🐾
Author: unknown
Artist: The Old Shepherd's Chief Mourner-Edwin Landseer 1837.


Love this 🐾
05/01/2024

Love this 🐾

😆🐾🐾

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