
20/06/2025
Some more information on the effects of glyphosate. Definitely good for you to consider whether these are risks you want to accept for you or your horse.
Glyphosate, a widely used herbicide, has been shown to affect various metabolic processes in both plants and animals, potentially leading to adverse health outcomes. It can disrupt metabolic pathways, including those related to amino acids, carbohydrates, nucleotides, and lipids, and may also contribute to oxidative stress and endocrine disruption.
Effects on Metabolic Pathways:
Amino Acid Metabolism:
Glyphosate can reduce the levels of certain amino acids, such as glycine and glutathione, and impact arginine metabolism.
Carbohydrate Metabolism:
Glyphosate can affect carbohydrate metabolism, potentially leading to changes in glucose levels and energy production.
Nucleotide Metabolism:
Glyphosate can disrupt nucleotide metabolism, particularly purine synthesis, resulting in reduced levels of deoxyguanosine and other purine-related compounds.
Lipid Metabolism:
Glyphosate has been linked to lipid metabolism disorders, potentially leading to health risks.
Effects on Energy Metabolism:
Mitochondrial Dysfunction:
Glyphosate can impair mitochondrial function, which is crucial for cellular energy production.
Oxidative Stress:
Glyphosate can induce oxidative stress, leading to cellular damage and contributing to metabolic disruptions.
Energy Metabolism Disruption:
Glyphosate can interfere with energy metabolism pathways, potentially affecting how cells generate and utilize energy.
Other Effects:
Gut Microbiota:
Glyphosate can alter the composition and function of the gut microbiota, which plays a vital role in various metabolic processes.
Endocrine Disruption:
Glyphosate exposure has been linked to endocrine disruption, potentially affecting hormone levels and impacting reproductive health.
Insulin Resistance:
Glyphosate consumption has been associated with an increased risk of insulin resistance, a condition linked to type 2 diabetes.
Potential Health Implications:
The metabolic disruptions caused by glyphosate can contribute to various health issues, including:
Liver Disease:
Glyphosate exposure has been linked to liver inflammation and metabolic disorders, potentially increasing the risk of liver cancer, diabetes, and cardiovascular disease.
Intestinal Diseases:
Glyphosate-induced changes in the gut microbiota can lead to intestinal dysbiosis, potentially contributing to diseases like Crohn's disease.
Neuropsychiatric Conditions:
Glyphosate has been linked to neuropsychiatric conditions, potentially through its impact on gut microbes and metabolic pathways.
Further Research:
While research suggests potential adverse effects, more research is needed to fully understand the long-term health consequences of glyphosate exposure and its impact on various metabolic processes.