27/07/2024
An interesting article on faecal microbial transplantation.
FMT, Faecal Microbial Transplantation, is now the only probiotic I reach for.
This is my first in a series of posts on FMT I'm calling "Eat s**t and live" (that is literally the greatest tag line ever thought of, thank you Moddie Lambert!!!), largely as I'm having so much success with it I need to tell everyone.
Here's the short of it, and as I will highlight at Dr. Judy Morgan's forthcoming conference in Orlando in October, my journey with probiotics is something like a bell-shaped curve - "ooh what are these" at the start, "OH MY GOD THESE ARE AMAZING I'M GOING TO USE THESE EVERYWHERE" at my zenith and now tapering off to occasionally, the more knowledge I accumulate and the better solutions that are presented to me.
While yes, the data still suggests over-the-counter probiotics can and should be used to get you out of hole, in the fact of bad gut upset say, or maybe with antibiotics (though even then the longer term studies are now highlighting a few issues. One is the gut flora struggles to get back to normal when they are deployed, in that it takes it longer to do so).
But on reflection, and somewhat unsurprisingly, the gut biome is complicated. A 1000 different species of bacteria, oodles of yeasts, fungi and untold viruses and bacteriophages (and yes, maybe even a few parasites) all happily living together in an enormous (to them) hustling and bustling city.
Then you come along and move in a small handful of species made in a lab - we didn't want 100 plumbers, we needed 500 electricians, sort of thing.
So the biome is complex. This is where FMT comes in. In essence, they get gut flora from a very healthy dog and stick it in an unhealthy dog and boom the patient recovers.
As always, the method they've been using for 1000s of years works best.
FMT dodges the issues with over-the-counter probiotics. They include ALL the oxygen-loving bacteria (can't make a probiotics for the anaerobes, sadly). So it's all the good guys, a complete reset.
And the studies behind its usage, compared to antibiotics or probiotics, are highly impressive. Patients recover quicker from infection and gut flora returns to normal faster when compared to the other two. Moreover, it offers REAL resolution to patients with IBS, IBD, ulcerative colitis, all those sorts of issues, no joke. Have a Google and you'll find 100's of studies marking very large percentage gains for gut issues when using FMT over standard therapies.
But it's all the other little cool findings. Like you can take gut flora from an anxious mouse and put them in a calm mouse and make him anxious (and vice versa, heads up folk with dogs chronic anxiety), they can take the gut flora from fat mice and put them in skinny mice and they get fat (and vice versa...know a skinny friend?! Just ask them to poo in a cup...) and recently, they discovered that they can take gut flora from Alzheimers humans or mice and put them in mice destined to get the disease and BOOM it kicks (they cut the vagus nerve, linking the gut to the brain in some of the mice who then didn't develop the disease, to prove the link).
In summary, I love the idea of using food / prebiotics to grow the groups you want in there, that's top of my list for sure, not popping in probiotics on the blind. But if I have a dog in real need, just terribly inflamed, chronic IBS/IBD that's been going on ages, I now recommend first trying S.boulardii (a probiotic yeast) to see if that helps rest the gut flora but it's 50/50 if that will work in tricky cases. I'm really saying that to buy time until their Legacy Biome capsules arrive from the US.
The testimonials I'm now getting from some close-to-lost causes are unbelievable, and I'll share them with you and a few of the more exciting studies in future posts.
If you have a dog suffering chronic gut issues or IBD (or chronic skin issues that swabs show you are not yeast-related as, if yeast related, you can fix topical issues with ProPythium quicker and cheaper or, if internal yeast, with bits from the local health shop, see my new "yeast" article on dogsfirst. ie) or a dog suffering chronic anxiety or hard-to-explain fear reactions (IBS), one that you haven't been able to restore with good diet and some natural additions, I urge you to try FMT.
I used to recommend you get the gut flora checked in these dogs but increasingly I recommend they spend that money on the actual treatment, particularly when I'm sure there's a likely dysbiosis fuelling the issue.
See links below to the product I use with 15% discount.
Hope it works. When it does, please let us know.