
15/04/2025
I had a nice case recently which was a lesson in being prepared to change plans mid-stream. A lovely spaniel (not the stock photo below!) presented with long term upper GIT diarrhoea, weight loss, watery faeces, no tenesmus, no mucus, hypoproteinemia, hypocholesterolemia. Various diets including a HA diet had been tried to no avail. Prednisolone had helped only a little. But in conversation with the owner, she disclosed that melena had been observed, but this had not been mentioned to the primary care vets.
Abdominal ultrasound showed a markedly irregularly thickened colon and enlarged adjacent lymph nodes, but the colon had not been prepped for colonoscopy. Normally, I would not countenance this, but the diarrhoea was so watery that it seemed reasonable to give colonoscopy a go after the prior ultrasound-guided LN FNAs, the gastroscopy and the duodenoscopy. Results were surpisingly good!
In the videos below, note the impression of stunted villi in the duodenum, and the grossly thickened colonic mucosa. All biopsies showed severe inflammatory change, and the patient is greatly improved on prednisolone and ciclosporin. Next stop further dietary trials, and maybe the delights of Faecal Matter Transplant!