Astaria Global's patented Alpha2EQ
(1)
...stem cell and physical therapy represent promising strategies for tendon repair. Recognizing the clinical signs, contacting your veterinarian, and getting appropriate treatment and rehabilitation plans in place will ultimately lead to the fastest recovery.
Learn how to recognize a tendon injury and what you and your veterinarian can do to treat it.
Several treatment options are available for tendon injuries, yet no singular “one-size-fits-all” therapy currently exists. Researchers have described significant success using mesenchymal stem cells to treat tendon injuries in racehorses, with the most notable statistic being a significantly reduced re-injury rate. Despite the exciting research around biologic treatments such as these, controlled exercise and physical therapy remain the most important cornerstones of tendon healing.
Learn how to recognize a tendon injury and what you and your veterinarian can do to treat it.
The study team described a fresh approach to treating these lesions, known as subchondral bone cysts. They postulated that they could promote and accelerate healing and bone recovery through implanting fat-derived mesenchymal stromal cells included in platelet-rich plasma, which is a source of growth factors.
A lame Thoroughbred that had never raced was able to train and launch a track career in Italy.
The diagnostic tests veterinarians use are evolving to improve how we manage infectious diseases in horses.
There is great interest in platelet-rich plasma in both human and veterinary medicine. Applications for platelet-rich plasma in dermatology, ophthalmology, musculoskeletal disease, and other medical fields are under investigation in the scientific community.
FDA announced it does not expect the developer of PrecisePRP Canine to submit an approval application because the risks are understood and mitigated.
Alpha2EQ® Editorial Comment: The Current State of the Use of Alpha-2 Macroglobulin as an Orthobiologic Dear Dr. Moira, What makes Alpha2EQ® unique? Astaria Global as the Leader with A
In total, 71 percent of racehorses treated with MSCs returned to racing following treatment and rehabilitation. The prognoses were similar for both the more-severe and less-severe lesions. For horses that had previously raced and returned to racing post-injury, researchers found no significant difference in the number of races, earnings or earnings per start.
In total, 71 percent of racehorses treated with MSCs returned to racing following treatment and rehabilitation
Alpha2EQ Today & Tomorrow! Alpha2EQ for the management of Equine Asthma Dear Dr. Moira, Please join us today as speakers Dr. Stuart Shoemaker and Dr. Dan Dreyfuss discuss the use of nebulizing
Alpha2EQ Alpha2EQ for the management of Equine Asthma Dear Dr. Moira, Please join us as speakers Dr. Stuart Shoemaker and Dr. Dan Dreyfuss discuss the use of nebulizing Alpha2EQ for the manageme
Researchers have learned more about equine dental-derived stem cells and potential ways these agents could help treat equine dental conditions.
Researchers have learned more about equine dental-derived stem cells and potential ways these agents could help treat dental conditions.
“We were so close to getting him back before,” Dawson told TDN. “If stem cells could bring anything to the party it could really make a difference. He's not terribly injured. He just has this on-going nagging-type issue and so we thought if we could get him healed he could race again and do so at a high level and win. That would make his stallion value a lot better. It's not a matter of dollars to me. I just want to get him into a situation where he has access to really good mares and therefore get him to a level playing field to produce great offspring. If you're covering mediocre or less-than-mediocre mares your stallion career is going to be pretty short.”
Dawson has now decided to pursue another attempt returning the Kentucky Derby winner to the races, this time enlisting the help of stem cell therapy.
Overall, they found regenerative medicine based on cell therapy to be highly effective in osteoarticular injuries in horses due to the regenerative and anti-inflammatory properties of these therapies, making them a promising alternative for the treatment of musculoskeletal injuries in horses.
Regenerative therapies involve the use of living cells and non-cell therapies to treat various diseases, injuries, and medical conditions to restore affected tissue to its native state.
Learn about serum amyloid A and how veterinarians can use it for early identification of inflammation in horses.
Alpha2EQ The Power of Alpha-2-Macroglobulin Dear Dr. Anna, Alpha2EQ® Kit: Hard to believe that Fall is here! Hope everyone had a great, busy summer! When I speak with veterinarians, I am often a
If you’ve ever considered your horse to be your “better half,” you’re not alone.
If you've ever considered your horse to be your “better half,” you’re not alone. Norwegian and American researchers recently found that riders and horses can enter into a unique state of interspecies "co-being" with one other.
Treatment of SDFT core lesions in horses has evolved substantially over the past 2 decades, particularly regarding biologic therapies such as stem cells, rehabilitation treatment modalities, and controlled rehabilitation protocols. The purpose of the current manuscript is to focus on the use of MSCs for the treatment of SDFT core lesions, and as such, other treatments will not be discussed.
Abstract The purpose of this manuscript, which is part of the Currents in One Health series, is to take a comparative approach to stem cell treatment for tendon injury and consider how the horse might inform treatment in other veterinary species and humans. There is increasing experimental and clini...
Mesenchymal stem cells (MSCs) are self-renewing stromal cells that can be isolated from several sources, including the umbilical cord, fat, and bone marrow.
These mesenchymal stem cells might be a highly effective treatment option in horses with osteoarthritis.
Alpha2EQ Alpha2EQ® Advanced, Patented, Proven Technology Dear Dr. , Alpha2EQ® Kit: Alpha2EQ is a potent biological and anti-inflammatory molecule, taken from the horse, that addresses equine lameness,
Recent progress in EV research has provided evidence that EVs from a variety of cell sources can stimulate the proliferation, differentiation, and rejuvenation of cells from musculoskeletal lineages including osteocytes, myocytes, chondrocytes, tenocytes, and fibroblasts in vitro. Subsequent in vivo studies have demonstrated that EVs enhance the repair and regeneration of bone, skeletal muscle, and cartilage in rodent models. The therapeutic use of EVs for musculoskeletal regeneration in veterinary companion animal species is still an emerging area of research. The limited work in this area to date has provided evidence of safety; however, well-designed prospective studies evaluating larger numbers of animals will be required to fully evaluate the clinical efficacy of EV therapeutics. To translate EV therapeutics to the clinic, strategies to scale up EV production, standardize isolation and purification methods, and store EVs long term are a current area of research requiring more investigation. Finally, the ability to modify EVs for the development of customized and personalized therapeutics makes EVs a promising tool for future veterinary use, especially as precision medicine initiatives become more widespread in veterinary medicine.
In recent years, extracellular vesicles (EVs) have emerged as prominent mediators of the homeostasis, repair, and regeneration of musculoskeletal tissues including bone, skeletal muscle, and cartilage. Accordingly, the therapeutic potential of EVs for regenerative medicine applications has not gone....
Alpha2EQ Alpha2EQ® Advanced, Patented, Proven Technology Dear Dr. , Alpha2EQ® Kit: With Summer fast approaching, I thought I would take a moment out of your non-stop schedules and remind you of a grea
As a result of repetitive loading during work, subtle damage to ligament fibers can occur and accumulate over time. So, what happens when this important structure gets injured? In this case study we will follow a suspensory ligament injury in a young Quarter Horse mare named Happy, diagnosed and treated at Colorado State University, where I am a resident in equine diagnostic imaging.
A young Quarter Horse reiner undergoes treatment for a left-hind proximal suspensory ligament injury.
The advantage of using orthobiologics is that they help to heal the damaged tissue more effectively, so the result is much closer to the original elastic form found in ligaments and joints. Aseptic precautions such as shaving and sterilizing the skin surface above the joint or tendon are prioritized to prevent infection.
Stem cells, platelets and serum can be reinjected into an injured joint or ligament to improve healing in horses, says Dr Mac.
Researchers have suggested the secretome of synoviocytes (biofactors secreted by cells lining the joint) contains mediators that can protect cartilage from the degenerative effects of interleukin-1 beta (IL-1β), a highly potent inducer of cartilage degradation in horses with osteoarthritis.
This biologic could have a protective role as a disease-modifying product for horses with osteoarthritis.
Mesenchymal stem cells (MSCs) are self-renewing stromal cells that can be isolated from several sources, including the umbilical cord, fat, and bone marrow. Pradera-Munoz said researchers have shown the key advantages of using umbilical-cord-derived MSCs over other sources in regenerative joint therapy.
These mesenchymal stem cells might be a highly effective treatment option in horses with osteoarthritis.
Alpha2EQ-15 New Alpha2EQ-15® Dear Dr. , ALPHA2EQ-15 ARRIVES March 15th!!!! Now ALL your clients can have access to an advanced, proven regenerative technology. If you have additional questions or wou
Alpha2EQ Alpha2EQ® Best Practices for Joint Therapy Dear Dr. , Alpha2EQ® Kit: You may have missed the AAEP Conference in Texas in 2022. Alexandra Beckstett, Managing Editor of “The Horse” Magazine has
Canadian researchers have found that using equine pooled cryopreserved umbilical cord blood in mesenchymal stem cells (MSC) has proven to be safe and effective in treating joint pain and inflammation.
Research shows the value of using equine pooled cryopreserved umbilical cord blood in mesenchymal stem cells for treating joint pain and inflammation in horses.
Biological treatments such as mesenchymal stem cells (MSCs), platelet-rich plasma (PRP), and interleukin-1 receptor antagonist protein (IRAP) aim to further improve healing quality to make the developing tissue more like tendon tissue than scar tissue, according to Smith. After 20 years of use, MSCs still show the best results in SDFT repair, though they do not prevent re-injury in every case. They appear to work better in the worst-affected horses. Re-injury rates are about 50% lower in racehorses and sport horses treated with MSCs than in control groups treated with saline. Allogeneic MSCs (which come from another horse) are more convenient and less expensive than autologous (from the patient) ones, he said, and initial study results suggest they might be just as effective.
At the 2022 BEVA Congress, one presenter discussed the challenges associated with SDFT injuries, plus potential solutions.
Alpha2EQ Specials WHAT IS ALPHA2EQ®? Dear Dr. , Alpha2EQ Kit: WHAT IS ALPHA2EQ® Orthobiologics: What are they and why are they important? Orthobiologics are derived from natural substances found in th
Now we can use orthobiologics to provide the best possible healing with maximal function. All orthobiologics use the body’s natural physiologic processes to reduce inflammation and facilitate the repair of injured tissues. The goal is to provide a better “heal” that allows the horse to function better and have a longer career.
The key concepts behind 6 orthobiologics available to equine veterinarians.
9657 Kelly Bridge Road
Dawsonville, GA
30534
Be the first to know and let us send you an email when Equine Partners America posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.
Send a message to Equine Partners America:
All Animals Veterinary Hospital
Auraria Road
