The Perseus Foundation

11/19/2025

📣Giving pet parents an edge in the fight against canine cancer. According to early data, IDEXX Cancer Dx™ testing can detect lymphoma before clinical signs are present.

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11/17/2025

T-cell therapy is an emerging, experimental treatment for canine lymphoma that uses the dog's own immune cells, or modified human cells, to target and kill cancer cells. Unlike traditional chemotherapy, it works by harnessing the power of the immune system to fight the cancer. Current approaches include using the dog's own T-cells, which are collected, expanded, and reinfused, or using genetically engineered human CAR T-cells, which are injected directly into lymph nodes. This is a developing area of research, not yet a standard treatment, and is being explored more for B-cell lymphoma.

How T-cell therapy works

Patient's own T-cells: Healthy T-cells are collected from the dog's blood.
These T-cells are then selected, expanded (grown in a lab), and "primed" to recognize and attack the cancer cells.
The activated T-cells are then reinfused into the dog.
Engineered human T-cells: Another approach involves using genetically modified human CAR T-cells.
These T-cells are "trained" to target specific cancer cells.

In some cases, they are injected directly into the dog's lymph nodes, not just the bloodstream.
This method is being studied to see if it can be used off-the-shelf for various dogs, rather than being made specifically for each one.
Current status and considerations

Experimental and developing: T-cell therapy is still experimental and not a routine treatment for cancer in dogs. It is primarily being used in clinical trials to gather more data.
Combination therapy: Researchers are investigating the best way to combine it with existing treatments like chemotherapy (e.g., CHOP).

B-cell vs. T-cell lymphoma: Studies are exploring if it is more effective for certain types of lymphoma, such as B-cell lymphoma.
Limitations: The success of a patient's own T-cell therapy can be affected by the dog's size and blood supply, as a significant amount of blood is needed for the procedure.
Prognosis: The prognosis for canine T-cell lymphoma is often shorter than for B-cell lymphoma, but T-cell therapy aims to improve survival rates for both.
Advancing research: The research in dogs is also informing the development of CAR T-cell therapy for humans with lymphoma.

11/17/2025

We love you Max ❤️🔔🥳

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Six months ago, we heard the words no dog parent ever wants to hear: “It’s cancer.”

When Max was diagnosed with lymphoma at just 4 years old, our world stopped. But his didn’t. Through every chemo session, this brave boy wagged his tail. Through every rough day, he still brought us his favorite toy.

Today, Max rang the bell at the vet clinic. He’s officially in remission.

Staffys are fighters. They don’t know how to give up. Max taught me that strength isn’t about never being afraid - it’s about facing each day with courage, no matter what.

To every pet parent fighting this battle right now: there IS hope. Keep fighting. They’re worth every single moment.

11/17/2025

INNOVATIVE TREATMENT, LIFE-CHANGING CARE FOR OUR PETS.

Heartfelt thanks to PetCure Oncology for their excellence in care. 💙 🐾❤️

Stereotactic radiation (SRS/SRT) is an advanced form of radiation therapy that has already been proven effective in treating humans with cancer. What sets SRS/SRT apart is its powerful and unprecedented precision, which now enables the treatment of some tumors that were previously considered untreatable.

SRS/SRT is a non-surgical therapy that puts a premium on your pet’s quality of life, resulting in far fewer treatment sessions, anesthetic events and side effects. 🐾🦴🐾

11/17/2025

Meet Shiro! 🐾 This 10-year-old Labrador was treated for a multilobular osteochondrosarcoma of the maxilla by the PetCure Oncology Team at Thrive Pet Healthcare Specialists - San Antonio.

Shiro, a Japanese name signifying valor, fits you beautifully. 🧡🤍💙

PetCure Oncology as always, heartfelt thanks from our team for your outstanding care snd vidion.

11/17/2025

World, please say hi to adorable Mookie! 🐾

Mookie, 10-years young underwent treatment for a trigeminal nerve sheath tumor using stereotactic radiation by the PetCure Oncology Team at Veterinary Radiosurgery and Imaging Center, Clifton, NJ.

Warmest Congratulations, sweet Mookie! 🎉 👏🥳

11/15/2025

We love hearing the news !🐾🗞️❤️:

November is Pet Cancer Awareness Month, and Oban is one of our oncology clinical trial stars. 💛 Since March, this sweet boy has been visiting CSU as part of a national study testing a new treatment for oral melanoma. While the treats are still his favorite part, he’s also helping advance care f...

11/14/2025

While geared to members of the Veterinary Oncology Community this is a very interesting and informative read. 🐾🐶🐾

“We can’t diagnose with our eyeballs.” 👀 That’s one of the key points I shared in this week’s Vet Blast Podcast with Dr. Adam Christman—and it’s something I remind myself and others often. As veterinarians, we see so many lumps and bumps every day. But skipping a fine needle aspirat...

11/13/2025

Thank you Oncovet PR for your outstanding care of Cherube. ❤️

Summary: Querube was diagnosed with Large B-Cell Lymphoma and is following the CHOP protocol. We are so happy he is in total remission.

Complete or total remission means that all signs and symptoms of a disease, like cancer, have disappeared according to medical tests, which include physical exams, blood tests, and scans. This is also known as "no evidence of disease" (NED). While it is a significant and positive sign, it does not guarantee a cure because some cancer cells may still be present and could potentially become active again in the future, which is called a recurrence.

Background:

🐶 Aquí con este guapo que se llama Querube, una bolita de energía y ¡el más bueno! 🩵

Querube tiene Large B-Cell Lymphoma y está recibiendo quimioterapia con el protocolo CHOP, considerado el gold standard para este tipo de cáncer. 💉🎗️

Entró en remisión completa después de su primera dosis 🙌🏼 y ha tolerado la quimioterapia perfectamente bien, sin ningún efecto secundario. 🌟

Le pusieron de nombre Querube en honor a la balada puertorriqueña interpretada por Danny Rivera. 🎶🇵🇷

Aunque suene medio raro, el linfoma es uno de mis cánceres favoritos para trabajar. Vemos al paciente y a su familia prácticamente todas las semanas por 15 semanas como parte del protocolo, y terminamos creando un lazo súper especial con ellos. Siempre acompañándolos desde el principio hasta el final.🩵🐾

11/12/2025

11/12/2025

Warm congratulations sweet Milo 👏 We are rooting for you❤️😘🐾!!!

Thank you SAGE Veterinary Centers for your excellence in care.

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Meet Milo! 🐾 This 8-year-old Beagle was treated for a progressive facial mass with stereotactic radiation (SRS/SRT) by the PetCure Oncology Team at SAGE Veterinary Centers

Milo was just told that his graduation party will be next door at the PetHero Hall of Fame 🎪

Congratulations, Milo! 🎉

👉 Drop a 🎪 or 🐶 to congratulate Milo

11/11/2025

🌟 🎊Happy Veterans Day! 🇺🇸 Today, we honor our courageous veterans and their commitment to our freedom. We salute not only the brave individuals but also the Military and Contract Working dogs who stand by their side. A ❤️ thank you for your service. 🐾❤️🐾💙🐾