25/06/2022
Pibble Dobie Lovin! Besties đ
A page all about ME, No Sushi Sasha; The Flying Pibble & my Buck Wild Crew! Defying labels & expecta
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Pibble Dobie Lovin! Besties đ
Cancer warrior! Iâm done with radiation! đđ I told da hoomans âItâs Swim time!â (I tell âem that erryday tho.) Thank you for exceptional care so I could get back to swimming! đ
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Sasha has an osteosarcoma tumor on her skull ( #5). Anyone whoâs dealt w/ & has knowledge about immunotherapies like the Yale HER2/EGFR vaxx or the Penn HER2/neu vaxx, Palladia, targeted drugs like Sirolimus etc in canine osteosarcomaâ pls DM me. đ
I know a fair bit about canine oncology but my knowledge & experience is limited to soft tissue sarcomas, carcinomas & apocrine gland adenocarcinoma. I donât know much about bone tumors or osteosarcoma. Would be grateful of any helpful advice, research etc.
Xx Thank you! đđ
Topic: Testing & Targeted Drug Therapy - Whatâs that?
performs genetic testing of a dogâs tumor after surgical resection. The testing provides more information on the tumors genetic features which pathology do not contain. For example, mammary carcinoma features differ greatly from case to case.
Whyâs it helpful to know what genes are upregulated, if hormone receptors are present & the specific genetic features of a tumor?
Because this information can identify specific therapeutic targets. It can tell you about the tumorâs sensitivity to chemo & identify small molecule inhibitors, tyrosine kinase inhibitors, immunotherapies & hormone receptor inhibitors of therapeutic benefit. Ex: the estrogen inhibitor, Tamoxifen can be very effective on mammary carcinoma thatâs estrogen receptor+ but not estrogen receptor- tumors. Having this info can make other treatments & therapies available to your dog that otherwise wouldnât be. Veterinary oncologists can create a targeted drug therapy cocktail to your dogâs tumor from the Fidocure report.
rescued Baily 4/28/18 from w/a giant mammary tumor already MET to her lungs. Dr Linderman crafted a targeted drug cocktail [Tamoxifen, Deramaxx, Sirolimus] & enrolled her in clinical trial of a HER2/EGFR cancer vaccine based on her genetic testing report. Bailyâs highly targeted treatment protocol prolonged her life from the initial prognosis of just 3-6mos to 22mos w/o any negative effects to quality of life. đđ
To get testing, you have to tell your dogâs Veterinarian to request it. If you didnât do so pre-op, it may still possible to request. It depends on whether or not the tissue sent to the pathologist is still available.
If your Vet is unfamiliar w/ direct them to Fidocure.com
Swipe to see what testing reports look like. #2-6 are 2 of Piperâs reports 2020 & 2022. #7-9 is Bailyâs Innogenics Report 2018 (pre-Fidocure availability).
Piper finished Chemo! đ Diagnosed w/a**l gland cancer (AGASACA) Jan 2020, remission Apr 2020, recurred Sep 2021, remission Apr 2022âŚ
What is AGASACA? âApocrine Gland A**l Sac Adenocarcinoma is a highly aggressive cancer in dogs. A tumor develops on the a**l glands & spreads quickly & often unnoticeably. Itâs often caught late; already metastatic to lymph nodes or other organs.
Piperâs AGASACA was serendipitously found on imaging for an unrelated mammary tumor. PET scan to see if the mammary tumor had spread to before surgery found no signs of metastasis from the mammary tumor.
Butâ the scan showed cancer in lymph nodes at her hind end. Her DVMs did another re**al exam suspecting an a**l gland tumor & found a tiny BB sized tumor. As small as the tumor wasâ it had already spread to the sub-lumbar lymph nodes. And why this cancerâs often discovered at late stages.
successfully removed the mammary tumor, the a**l gland tumor & the cancerous lymph nodes. Piperâs original reason for seeing â the Mammary tumor turned out to be low grade & surgery was curative. While the AGASACA was a different storyâŚ
We wouldnât have known Piper had AGASACA until much later but for the lucky happenstance that imaging for an unrelated cancer, discovered it.
Weâre going to share more in a series of posts about , , oncology care, testing, , dog cancer diet, canine clinical trials, immunotherapies, cancer vaccines, targeted drug therapy, supplements & more.
Pls feel free to DM if you need advice or help navigating canine cancer. Weâre happy to share our knowledge & direct you to research, expertise & sources. đ
Sending Fur-hugs & Fur-love, đ
**lglandcancer
Derp DaysâŚ
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Derp-A-Derp Love from my heart to yours. â¤ď¸ Love you always my angel pibble, Patchy. âžđ . #derp #derpaderp #pibblesfly #foshizzledapibble #myheart #morethanmybreed #pibbles #pitbulls #rescuedog #adoptdontshop #martialarfs #shelterdog #pitbulllove #happydog #dogs #dogvideo #cutedogs #mydogmakesmesmile #happydoggo #PatchyBaby #seniordogsrule #adoptaseniordog
Zara Just Wants Love & A Home! đ Will you help her find it? Please share Zara. She is so deserving. Zara fka Junebug is in a foster home through @reboundhounds w/ awesome foster mama @gailpowell3663 â¤ď¸ Contact Gail or #reboundhounds on instagram or [email protected] . To learn more about Zara, go to reboundhounds.org or search hashtags #InLoveWithTheBug #ZaraOnTheRebound . #rescuedog #pibbles #adoptdontshop #findingFurever #NeedAHome #fosterdog #rescuedogsofinstagram #TheDodo #ShareMe #LoveMe #AdoptMe
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VOL UPâď¸- ADOPT JUNEBUG! All Junebuggie wants is LOVE! Pls HELP find her a forever home by sharing! Sheâs so deserving of one, the sweetest, easiest dog who is eager to please. She needs a solo dog home but isnât dog reactive at all. She can be selective and afraid of some dogs at some times. On the leash sheâs a dream & pays dogs no mind at all. Adult only or Teenage Kids & up, only because she can afraid at times, trembling & shaking, which younger kids may not understand. She has been around lots of kids & ppl under the supervision of her foster & Buggie loved the affection. Sheâs such a sweet loving dog! #InLoveWithTheBug . To learn more please contact @reboundhounds Reboundhounds.org [email protected] . . #rescuedog #reboundhounds #Junebuggie #TheDodo #AdoptADog #rescuedogsofinstagram #adoptables #cutevideos #morethanmybreed #adoptdontshop #rescuedogs #needahome #junebugontherebound
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