Last week, we celebrated the end of Ranger Dangerโs treatment! Ranger is the smiliest boy and weโre so proud of him! ๐๏ธ๐
Mary is a true cancer warrior โ not only is she fighting a tough battle but sheโs also helping researchers find new ways to fight her rare form of cancer.
DIPG is deadly form of cancer - only about 300 children are diagnosed in the US each year. Funding and treatment options remain limited. Mary is on a clinical trial using CAR T cells to help fight the disease - a similar approach to a study we have here at the FACC.
And so far, itโs working! Mary has outlived her prognosis and is still curious, funny, and has a big heart. Weโre sure sheโs one of the best veterinarians on the team.
Thanks to all at the @csuvethospital for letting Mary join their services.
#marystrong #dipg #dipgawareness
Happy Thanksgiving.mp4
From our family to yours, we hope you have a wonderful Thanksgiving!
In this season of gratitude, let it be known that we are incredibly thankful for our supporters, collaborators, team, and clients who make our work possible.
Thanks to a special dog named Lucy, we have some of the most advanced imaging equipment in veterinary medicine.
Jeffrey and Tiffany Neu, Lucy's humans, have made both the Lucy & Friends CT and the Lucy & Family PET/CT Suites possible with their generous donations.
Watch this video to gain a better understanding of the impact Lucy has had on the hospital and will continue to have for years to come:
Lights, camera, action! Canine cancer research is in the spotlight! ๐ฅ
Dr. Thamm was awarded the 2023 Alan Kelly International Award for The Kennel Club UK International Canine Health Awards. This award recognizes Dr. Thamm's canine cancer research, and his efforts to improve canine health and well-being.
Thanks to WUI Productions for profiling Dr. Thamm's work and this award.
Supporting Breast Cancer Survivors (1)
Cancer research comes in many different forms. Jennifer Currin-McCulloch, PhD, LSW, assistant professor of social work at CSU, and Lori Kogan, PhD, professor of clinical sciences at CSU have partnered with Linda Cook, PhD, associate director for population sciences in the University of Colorado Cancer Center to look at the convergence of companion animals in the case of a human breast cancer diagnosis.
During #NationalCancerMonth, itโs important to remember the human side of the diagnosis. This project has been especially important to give resources to cancer fighters.
Learn more about this collaboration here:
Drs. Boss, Karam, Dow
Collaboration is a crucial part of cancer research and during #CancerResearchMoonth, weโre proud of our collaborative efforts with University of Colorado Cancer Center to develop new treatment strategies that can be rapidly and safely studied in pet dogs to inform studies in people.
One of our current collaborative projects is studying the similarities between human and canine sinonasal carcinomas.
There is abundant canine research about sinonasal carcinomas, but much less available on the human side. In this collaborative research project, researchers are establishing canine sinonasal carcinoma as a translational model for sinonasal carcinoma treatment involving radiation and immune therapy for humans.
Dr. Keara Boss and Dr. Steve Dow from CSU are working with Dr. Sana Karam of CU to use the available canine studies to do a comparative analysis of treatments and outcomes to inform care for all species.
Watch this video to learn more:
Drs. Gustafson, LaBarbera
Daniel Gustafson, PhD of Colorado State University, and Daniel LaBarbera, PhD of CU are collaborating on an osteosarcoma project. Their work centers around studying a novel enzyme inhibitor โ CHD1L (Chromodomain Helicase DNA-binding protein 1-Like). They are studying the effectiveness of CHD1L inhibitors in human and canine cancer.
The study seeks to understand how effective the CHD1L inhibitors are in both human and canine osteosarcoma cells. Preliminary work shows that these inhibitors can be effective against osteosarcoma cells in humans and canines, which means that targeted therapies may work for both species.
During #CancerResearchMonth, weโre proud of our collaboration with University of Colorado Cancer Center.
Watch this to learn more:
Drs. Duval, Costello, Joshi
During #NationalCancerResearchMonth, weโre highlighting our collaborative research projects with University of Colorado Cancer Center.
One project is working to identify the essential genetic drivers in canine osteosarcoma. Collaborators from CSU and CU are working together to identify biological dependencies in canine osteosarcoma using whole genome CRISPR-Cas9 libraries. In the course of this project, researchers will be screening every single gene in the canine genome to better understand what genes are involved in canine osteosarcoma to systematically find new treatments.
Watch this video to better understand the project:
Sinonasal Carcinomas
Together, the Flint Animal Cancer Center, and the University of Colorado Cancer Center are collaborating to conquer cancer. We have four collaborative projects where researchers from each campus.
There is abundant canine research about sinonasal carcinomas, but much less available on the human side. In this collaborative research project, researchers are establishing canine sinonasal carcinoma as a translational model for sinonasal carcinoma treatment involving radiation and immune therapy for humans.
Dr. Keara Boss and Dr. Steve Dow from CSU are working with Dr. Sana Karam of CU to use the available canine studies to do a comparative analysis of treatments and outcomes to inform care for all species.
Watch this video to learn more about the project:
MRI
Special delivery! ๐๏ธ ๐๏ธ
This week, a brand new MRI machine was craned into the hopsital. We're thrilled to have access to this advanced imaging tool that is utilized for oncology patients as needed.
MRIs give us increased accuracy in diagnostics, staging and follow-up for our veterinary cancer patients.
The machine will be fully operational by mid-April.
Learn more about our diagnostic imaging team: https://buff.ly/3Z5jhSf
Darling Daisy
We're so proud of Daisy! ๐ผ ๐ผ
With all her energy and playfulness, you would never know she is fighting a heart base tumor. She's strong, resilient, and such a joy to work with!
threelegged dog
Large and giant breed dogs are the most at risk for developing a tumor of the bone called osteosarcoma. In the U.S., more than 10,000 dogs are diagnosed with osteosarcoma each year. Amputation remains the most common treatment for a bone tumor arising in a limb.
We have a new clinical trial that aims to determine the course of adaptation following limb amputation in dogs with osteosarcoma using an activity monitor.
This study will help us determine what pet owners can expect following an amputation.
Learn more about the study: https://buff.ly/3iZkSde
Biological Dependencies in Canine Osteosarcoma
Together, the Flint Animal Cancer Center and the University of Colorado Cancer Center are collaborating to conquer cancer. Weโve recently collaborated on four research projects with a PI at each campus.
Collaborators from CSU and CU are working together to identify biological dependencies in canine osteosarcoma using whole genome CRISPR-Cas9 libraries. In the course of this project, researchers will be screening every single gene in the canine genome to better understand what genes are involved in canine osteosarcoma to systematically find new treatments.
This project is managed by Dawn Duval, PhD, of Colorado State University and James Costello, PhD and Molishree Joshi, PhD of CU Cancer Center.
Watch this video to hear from the researchers:
The Flint Animal Cancer Center has worked closely with the University of Colorado Cancer Center for more than two decades. Together, we are partners in the worldโs most advanced comparative oncology research program. Through many collaborative projects, our scientists and clinicians work with their teams to develop new treatment strategies that can be rapidly and safely studied in pet dogs to inform studies in people.
Last year, FACC director, Dr. Rod Page, and his CU counterpart, Dr. Richard Schulick, announced a new collaborative initiative that awarded a total of $200,000 to four comparative oncology research projects. The projects were jointly funded and each includes a principal investigator from CSU and CU.
Watch this video to learn more about the projects and hear from the researchers themselves.
Read more about our collaboration to conquer cancer: www.csuanimalcancercenter.org/2023/02/03/collaborating-to-conquer-cancer